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26,27 Relative weight change at the 12-month time point was also compared using the Wilcoxon rank-sum test in patients who received concurrent ET and those who did not

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Histone acetylation and depression The first evidence of histone acetylations role in depression came from studies showing that HDAC inhibitors (HDACi), used alone or with antidepressants, enhanced antidepressant responses in animal models 139,140,141